Table 1.
Clinical characteristics at baseline of study participants
| All | DM | Non-DM | P-value | |
|---|---|---|---|---|
| Subject number |
237 |
73 |
164 |
NA |
| Age (years) |
54 ± 16 |
55 ± 17 |
52 ± 15 |
0.174 |
| Males |
165 (70) |
50 (68) |
115 (70) |
0.801 |
| BMI, kg/m2 |
25.2 ± 4.6 |
25.3 ± 4.5 |
24.8 ± 4.2 |
0.409 |
| LVEF, % |
53.9 ± 7.3 |
53.5 ± 7.1 |
54.2 ± 7.4 |
0.497 |
| Systolic BP (mm Hg) |
120 ± 21 |
123 ± 25 |
118 ± 23 |
0.134 |
| Diastolic BP (mm Hg) |
70 ± 9 |
69 ± 10 |
71 ± 12 |
0.215 |
| Serum creatinine, mg/dL |
0.80 ± 0.22 |
0.82 ± 0.21 |
0.78 ± 0.19 |
0.149 |
| Total Cholesterol (mmol/l) |
4.64 ± 1.05 |
4.56 ± 1.01 |
4.69 ± 1.09 |
0.387 |
| Triglycerides (mmol/l) |
2.23 ± 1.28 |
2.36 ± 1.65 |
1.97 ± 1.03 |
0.036 |
| LDL-C (mmol/l) |
2.87 ± 1.10 |
2.82 ± 1.13 |
2.91 ± 1.18 |
0.584 |
| HDL-C (mmol/l) |
0.98 ± 0.31 |
0.95 ± 0.22 |
1.01 ± 0.35 |
0.178 |
| HbA1c (%) |
6.5 ± 1.3 |
7.1 ± 1.2 |
6.1 ± 1.0 |
<0.001 |
| Glycated albumin (%) |
17.8 ± 7.6 |
21.2 ± 6.7 |
12.9 ± 4.5 |
<0.001 |
| Peak cTNI (ng/ml) |
37.3 ± 10.7 |
40.5 ± 11.4 |
36.2 ± 12.5 |
0.013 |
| Peak CK-MB (ng/ml) |
37.8 ± 15.6 |
39.4 ± 17.5 |
36.2 ± 16.4 |
0.176 |
| FBG (mmol/l) |
7.3 ± 2.8 |
8.8 ± 2.4 |
6.1 ± 1.7 |
<0.001 |
| Management of DM (%) |
|
|
|
|
| OHA |
|
25 (34.2) |
|
|
| Insulin only |
|
31 (42.5) |
|
|
| Insulin + OHA (s) |
|
17 (23.3) |
|
|
|
Risk factors (n, %) |
|
|
|
|
| Hyperlipidemia |
93 (39) |
32 (43.8) |
61 (37.2) |
0.334 |
| Hypertension |
95 (40) |
30 (41.1) |
65 (39.6) |
0.832 |
| Current smoking |
106 (45) |
30 (41.1) |
76 (46.3) |
0.453 |
| Family history |
29 (12) |
8 (11) |
21 (13) |
0.689 |
| Obesity |
55 (23) |
20 (27) |
35 (21) |
0.308 |
|
CGMS parameters on the first day |
|
|
|
|
| MBG (mmol/l) |
8.1 ± 2.6 |
10.6 ± 2.3 |
6.7 ± 1.1 |
<0.001 |
| MAGE (mmol/l) |
3.6 ± 2.0 |
3.9 ± 1.1 |
2.8 ± 1.6 |
<0.001 |
| SDBG (mmol/l) |
1.7 ± 1.0 |
2.5 ± 1.3 |
1.3 ± 0.7 |
<0.001 |
|
Angiographic data (n, %) |
|
|
|
|
| Single vessel |
92 (39) |
21 (29) |
71 (43.3) |
0.034 |
| Double vessels |
77 (32) |
27 (37) |
50 (30.5) |
0.324 |
| Triple vessels |
68 (29) |
25 (34) |
43 (26.2) |
0.207 |
| Main stem involved |
32 (14) |
12 (16) |
20 (12) |
0.378 |
| Multivessel | 145 (61) | 52 (71) | 93 (57) | 0.034 |
Data given as mean ± SD or n (%).
BMI, body mass index; LVEF, left ventricular ejection fraction; LDL-C, Low density lipoprotein-cholesterol; HDL-C, High density lipoprotein-cholesterol; HbA1c, hemoglobin A1c; CK-MB, creatine kinase-MB; cTnI, cardiac troponin I; FBG, fasting blood glucose; OHA, oral hypoglycaemic agent; MBG, Mean blood glucose; MAGE, the mean amplitude of glycemic excursions; SDBG, the standard deviation of blood glucose values.