Table 4.
Logistic Regression Modeling Results for Predicting Response in Patients with Acute Myeloid Leukemia and advanced Myelodysplastic Syndrome.
Variable | Odds Ratio (95% CI) | P Value |
---|---|---|
Univariate | ||
Beta-2 Microglobulin | 1.07 (0.98–1.18) | 0.122 |
Platelet Count | 0.999 (0.995–1.004) | 0.818 |
White Blood Cell Count | 1.01 (0.995–1.014) | 0.334 |
Age (<70 vs ≥ 70 yr) | 1.92 (1.06–3.48) | 0.032 |
Cytogenetics (Unfavorable Vs other) | 2.20 (1.28–3.78) | 0.004 |
Performance Status (<2 vs ≥2) | 1.65 (0.86–3.19) | 0.135 |
% Blasts in Blood | 1.01 (1.00–1.02) | 0.043 |
% Monocytes in Blood | 1.00 (0.98–1.02) | 0.877 |
% Lymphocytes in Blood | 0.99 (0.98–1.00) | 0.040 |
Hemoglobin | 0.88 (0.75–1.03) | 0.120 |
% Blasts in Bone Marrow | 1.01 (0.99–1.02) | 0.363 |
% Monocytes in Bone Marrow | 1.02 (0.98–1.06) | 0.315 |
% Lymphocytes in Bone Marrow | 1.01 (0.98–1.04) | 0.558 |
Blood Urea Nitrogen | 1.04 (1.01–1.07) | 0.014 |
Creatinine | 0.95 (0.76–1.20) | 0.671 |
Ch-Like Activity | 1.41 (1.14–1.76) | 0.002 |
Cas-L Activity | 1.21 (1.07–1.36) | 0.002 |
Multivariate | ||
Chymotrypsin-Like Activity | 1.44 (1.15–1.81) | 0.002 |
Cytogenetics | 2.36 (1.34–4.16) | 0.003 |
Age (<70 vs ≥70) | 2.03 (1.08–3.79) | 0.028 |