Table 5.
Logistic Regression Modeling Results for Predicting Survival in Patients with Acute Myeloid Leukemia and advanced Myelodysplastic Syndrome.
| Variable | Hazards Ratio (95% CI) | P Value |
|---|---|---|
| Univariate | ||
| Beta-2 Microglobulin | 1.07 (1.04–1.10) | <0.001 |
| Platelet Count | 0.999 (0.996–1.001) | 0.347 |
| White Blood Cell Count | 1.00 (0.997–1.007) | 0.486 |
| Age (<70 vs ≥ 70) | 2.09 (1.51–2.89) | <0.001 |
| Cytogenetics (Unfavorable vs other) | 2.30 (1.70–3.13) | <0.001 |
| Performance Status (<2 vs ≥2) | 2.14 (1.51–3.03) | <0.001 |
| Peripheral Blood Blasts | 1.00 (0.997–1.01) | 0.372 |
| Peripheral Blood Monocytes | 1.00 (0.99–1.01) | 0.870 |
| Peripheral Blood Lymphocytes | 0.997 (0.99–1.00) | 0.289 |
| Hemoglobin | 0.96 (0.89–1.05) | 0.397 |
| Bone Marrow Blasts | 1.00 (0.995–1.007) | 0.772 |
| Bone Marrow Monocytes | 1.00 (0.98–1.02) | 0.894 |
| Bone Marrow Lymphocytes | 1.01 (0.998–1.03) | 0.092 |
| Blood Urea Nitrogen | 1.05 (1.03–1.06) | <0.001 |
| Creatinine | 1.00 (0.91–1.11) | 0.939 |
| Ch-Like Activity | 1.21 (1.11–1.33) | <0.001 |
| Cas-L Activity | 1.12 (1.07,1.18) | <.001 |
| Multivariate | ||
| Cytogenetics (unfavorable Vs Other) | 2.35 (1.72–3.22) | <0.001 |
| Age (<70 vs ≥70) | 2.00 (1.44–2.79) | <0.001 |
| Performance Status (<2 vs ≥2) | 1.844 (1.29–2.63) | 0.001 |
| Blood Urea Nitrogen* | 1.026 (1.01–1.04) | 0.001 |
| Ch-Like Activity* | 1.20 (1.10–1.32) | <0.001 |
Used as continuous variables