Table 4.
Evaluation of effect heterogeneity among selected maternal and birth characteristics and childhood rhabdomyosarcoma histologic subtypes
| Characteristic | Embryonal RMS n=215 |
Alveolar RMS n=66 |
|||
|---|---|---|---|---|---|
|
| |||||
| ORa | 95% CI | ORa | 95% CI | p for heterogeneity | |
|
|
|||||
| Ever used any birth control | 1.19 | 0.80–1.79 | 1.41 | 0.75–2.62 | 0.624 |
| Using birth control when became pregnant | 1.51 | 0.59–3.90 | 1.13 | 0.23–5.40 | 0.706 |
| Spotting/cramping/abnormal vaginal bleeding | 1.80 | 1.10–2.92 | 2.49 | 1.25–5.00 | 0.357 |
| Anemia during pregnancy | 1.17 | 0.72–1.88 | 1.26 | 0.61–2.62 | 0.842 |
| Type of delivery | |||||
| Vaginal | 1.00 | Reference | 1.00 | Reference | |
| Cesarean | 1.60 | 1.00–2.56 | 1.18 | 0.53–2.63 | 0.449 |
| Birth weightb | |||||
| Normal (2,500g to <4,000g) | 1.00 | Reference | 1.00 | Reference | |
| LBW (<2,500g) | 1.64 | 0.62–4.32 | 4.46 | 1.41–14.1 | |
| HBW (≥4,000g) | 1.61 | 0.93–2.79 | 2.41 | 1.09–5.35 | 0.169 |
| Length of pregnancyc | |||||
| Normal | 1.00 | Reference | 1.00 | Reference | |
| Premature | 2.47 | 0.93–6.59 | 0.95 | 0.23–4.00 | |
| Overdue | 0.58 | 0.33–1.02 | 0.95 | 0.44–2.08 | 0.155 |
RMS = rhabdomyosarcoma; OR = odds ratio; CI = confidence interval; LBW = low birth weight; HBW = high birth weight
Adjusted for sex, age, and race.
Adjusted for length of pregnancy.
Adjusted for birth weight.