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. 2014 Jul 10;10(7):e1004462. doi: 10.1371/journal.pgen.1004462

Figure 5. Single-cell reconstruction of tumor phylogeny.

Figure 5

Maximum likelihood phylogenetic trees derived from single-cell genotypes at targeted somatic SNVs. (A) UPN461282 (B) UPN182896 (C) UPN288033. Values along edges represent branch support determined by non-parametric bootstrap (n = 1000 iterations). Edges with ≥75% support are considered strongly supported. Cell labels are identical to those in Figure 4 , and colored based on the presence variant clusters corresponding to the profiles detailed in Figure 4 .