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NAC loading prevents MWCNT-50-induced fetotoxicity. (A) After treatment with MWCNT-50 with and without NAC for 48 h, the MEFs were collected and the DNA was extracted. Nuclear DNA integrity was analyzed. (B) Brain deformity induced by a single dose of MWCNT-50 and MWCNT-50-NAC at GD 10.5 in p53−/− fetuses harvested at GD 17.5 (* p<0.05).
