Table 1.
Stem/progenitor cluster 1 (cryptorchid > wild-type, busulfan-treated; 88 probe sets)
| Row | Probe set | Accession no. | Gene | Description |
|---|---|---|---|---|
| 1 | 98783_at | Y15131 | Rbmy1a1 | RNA binding motif protein, Y chromosome |
| 2 | 102627_at | AF061569 | Igf2bp1 | Insulin-like growth factor 2 mRNA binding protein |
| 3 | 95063_at | AI606257 | Cdca7 | Cell division cycle associated 7 |
| 4 | 98108_at | X15789 | Crabp1 | Cellular retinoic acid binding protein I |
| 5 | 92290_at | Z19580 | Siah1b | Seven in absentia 1B |
| 6 | 101883_s_at | L22977 | Xlr3a /// Xlr3b | X-linked lymphocyte-regulated 3A /// X-linked |
| 7 | 92607_at | AF017994 | Mest | Mesoderm specific transcript |
| 8 | 161787_f_at | AV363418 | Cdt1 | Chromatin licensing and DNA replication factor |
| 9 | 93397_at | U56819 | Ccr2 | Chemokine (C-C motif) receptor 2 |
| 10 | 94743_f_at | M29009 | LOC214403 | Complement factor H-related protein |
| 11 | 100479_at | AA756653 | Dnmt3a | DNA methyltransferase 3A |
| 12 | 96169_at | AA683788 | Sall4 | Sal-like 4 (Drosophila) |
| 13 | 92208_at | AI152966 | C1qdc1 | C1q domain containing 1 |
| 14 | 160702_at | AA791885 | Rbm35a | RNA binding motif protein 35A |
| 15 | 103301_i_at | AA866668 | Sox3 | SRY-box containing gene 3 |
| 16 | 101853_f_at | M12660 | Cfh | Complement component factor h |
| 17 | 94761_at | X70058 | Ccl7 | Chemokine (C-C motif) ligand 7 |
| 18 | 161968_f_at | AV370035 | Ccr5 | Chemokine (C-C motif) receptor 5 |
| 19 | 104116_at | AW124049 | D5Ertd593e | DNA segment, Chr 5, ERATO Doi 593, exp |
| 20 | 93112_at | D86725 | Mcm2 | Minichromosome maintenance deficient 2 rr |
| 21 | 104576_at | AW212397 | Ski | Sloan-Kettering viral oncogene homolog |
| 22 | 96047_at | U63146 | Rbp4 | Retinol binding protein 4, plasma |
| 23 | 101160_at | X53798 | Cxcl2 | Chemokine (C-X-C motif) ligand 2 |
| 24 | 100325_at | M65027 | Gp49a | Glycoprotein 49 A |
| 25 | 92291_f_at | M29008 | Cfhr1 | Complement factor H-related 1 |
| 26 | 97444_at | AI844520 | Ifi30 | Interferon gamma inducible protein 30 |
| 27 | 93028_at | X58196 | H19 | H19 fetal liver mRNA |
| 28 | 102710_at | AF020313 | Apbb1ip | Amyloid beta (A4) precursor protein-binding |
| 29 | 97356_at | AI839653 | 1810008O21F | RIKEN cDNA 1810008O21 gene |
| 30 | 104680_at | AJ250489 | Ramp1 | Receptor (calcitonin) activity modifying protein |
| 31 | 161984_f_at | AV234303 | Col3a1 | Procollagen, type III, alpha 1 |
| 32 | 161698_f_at | AV232762 | Rprc1 | Arginine/proline rich coiled-coil 1 |
| 33 | 100397_at | AF024637 | Tyrobp | TYRO protein tyrosine kinase binding protein |
| 34 | 98817_at | Z29532 | Fst | Follistatin |
| 35 | 94982_f_at | AI852470 | Nme3 | Expressed in non-metastatic cells 3 |
| 36 | 103033_at | X06454 | C4b /// C4a /// | Complement component 4B (Childo blood g |
| 37 | 103075_at | M34381 | Pou5f1 | POU domain, class 5, transcription factor 1 |
| 38 | 162483_f_at | AV112006 | Col18a1 | Procollagen, type XVIII, alpha 1 |
| 39 | 101019_at | U74683 | Ctsc | Cathepsin C |
| 40 | 103981_at | AI842281 | U2af1-rs2 | U2 small nuclear ribonucleoprotein auxiliary |
| 41 | 97487_at | X70296 | Serpine2 | Serine (or cysteine) peptidase inhibitor, clad |
| 42 | 104237_at | AI838071 | Pcbd2 | Pterin 4 alpha carbinolamine dehydratase/di |
| 43 | 93538_at | AW228036 | Ttrap | Traf and Tnf receptor associated protein |
| 44 | 104337_f_at | AW208938 | Pkp2 | Plakophilin 2 |
| 45 | 104156_r_at | U19118 | Atf3 | Activating transcription factor 3 |
| 46 | 93041_at | D26089 | Mcm4 | Minichromosome maintenance deficient 4 h |
| 47 | 103534_at | V00722 | Hbb-b2 | Hemoglobin, beta adult minor chain |
| 48 | 103081_at | AA863928 | Baz1b | Bromodomain adjacent to zinc finger domain |
| 49 | 96083_s_at | AI226368 | Hnrpdl | Heterogeneous nuclear ribonucleoprotein D− |
| 50 | 103449_at | AA795923 | Lsm14b | LSM14 homolog B (SCD6, Saccharomyces cerevisiae) |
| 51 | 98092_at | AA790307 | Plac8 | Placenta-specific 8 |
| 52 | 96886_at | AW060556 | Stab1 | Stabilin 1 |
| 53 | 160458_at | AI853261 | Mcam | Melanoma cell adhesion molecule |
| 54 | 95627_at | AW046038 | Wwtr1 | WW domain containing transcription regulat |
| 55 | 96891_at | AI842771 | Anp32b /// LO | Acidic nuclear phosphoprotein 32 family, me |
| 56 | 97750_at | X06406 | Rpsa | Ribosomal protein SA |
| 57 | 94954_at | AI846628 | Anapc4 | Anaphase promoting complex subunit 4 |
| 58 | 103016_s_at | X68273 | Cd68 | CD68 antigen |
| 59 | 96138_at | AA682129 | Mars | Methionine-tRNA synthetase |
| 60 | 97199_at | AI854767 | Rbm12 /// Cpn | RNA binding motif protein 12 /// copine I |
| 61 | 95641_at | AI853899 | Plac9 | Placenta specific 9 |
| 62 | 98624_at | X75316 | Rnpc1 | RNA-binding region (RNP1, RRM) containin |
| 63 | 99475_at | U88327 | Socs2 | Suppressor of cytokine signaling 2 |
| 64 | 98059_s_at | D49733 | Lmna | Lamin A |
| 65 | 98088_at | X13333 | Cd14 | CD14 antigen |
| 66 | 95791_s_at | U14648 | Sfrs2 | Splicing factor, arginine/serine-rich 2 (SC-35 |
| 67 | 104524_at | AI842825 | Gltp | Glycolipid transfer protein |
| 68 | 92794_f_at | M35970 | Nme1 | Expressed in non-metastatic cells 1, protein |
| 69 | 103916_at | AI850713 | 8430420C20F | RIKEN cDNA 8430420C20 gene |
| 70 | 95944_at | AV299153 | Dhx36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 |
| 71 | 100468_g_at | X57687 | Lyl1 | Lymphoblastomic leukemia |
| 72 | 94839_at | M96823 | Nucb1 | Nucleobindin 1 |
| 73 | 98346_at | AI593759 | Lrrc54 | Leucine-rich repeat containing 54 |
| 74 | 100957_at | AA881160 | Ssbp1 | Single-stranded DNA binding protein 1 |
| 75 | 94024_at | AA671429 | Cdt1 | Chromatin licensing and DNA replication factor |
| 76 | 160182_at | AI846595 | Sfrs6 | Splicing factor, arginine/serine-rich 6 |
| 77 | 100732_at | X73829 | Rps8 | Ribosomal protein S8 |
| 78 | 98934_at | AI847513 | 0610007P06R | RIKEN cDNA 0610007P06 gene |
| 79 | 93089_at | X12507 | Eif4a2 | Eukaryotic translation initiation factor 4A2 |
| 80 | 103312_f_at | AW047929 | 2610101J03R | RIKEN cDNA 2610101J03 gene |
| 81 | 95657_f_at | AW125164 | D13Wsu177e | DNA segment, Chr 13, Wayne State University |
| 82 | 96710_at | AI854262 | H2afv | H2A histone family, member V |
| 83 | 104573_at | AA921069 | Bola2 | BolA-like 2 (E. coli) |
| 84 | 99336_at | U78085 | Rps5 | Ribosomal protein S5 |
| 85 | 99093_at | AI852864 | Rps10 /// LOC | Ribosomal protein S10 /// similar to ribosomal |
| 86 | 94767_at | U93864 | Rps11 /// LOC | Ribosomal protein S11 /// similar to ribosomal |
| 87 | 101129_at | X83590 | Rpl5 | Ribosomal protein L5 |
| 88 | 93092_at | U35323 | H2-DMa | Histocompatibility 2, class II, locus DMa |
Supplemental online Table 3 indicates overlap between stem/progenitor cluster 1 candidate genes (this table), stem/progenitor cluster 2, hematopoietic, neural, and embryonic stem cells and undifferentiated spermatogonia.