Table 1.
Analysis of horizontal basal cell-derived clusters after olfactory bulbectomy
| Cluster composition |
Total cells |
|||||||
|---|---|---|---|---|---|---|---|---|
| Animal | OE | Clusters | GBCs | ORNs | SUSs | GBCs | ORNs | SUSs |
| 1 | Control | 16 | 0.94 (0–10) | 8.13 (1–77) | 0 | 15 | 130 | 0 |
| Lesioned | 14 | 17.57 (0–213) | 126.79 (1–1,093) | 6.79 (0–94) | 246 | 1,775 | 95 | |
| 2 | Control | 7 | 1.86 (0–8) | 10.71 (1–38) | 0 | 13 | 75 | 0 |
| Lesioned | 11 | 9.27 (0–90) | 64.45 (1–611) | 4.73 (0–48) | 102 | 709 | 52 | |
| 3 | Control | 11 | 2.55 (0–20) | 24.18 (1–71) | 0 | 28 | 266 | 0 |
| Lesioned | 20 | 25.40 (0–302) | 130.75 (1–1,137) | 1.60 (0–15) | 508 | 2,615 | 32 | |
Unilateral olfactory bulbectomy was performed on three K5.CrePR1 tg/+: R26R+/− mice at 2 months of age, and mice were sacrificed 30 days later. Control OE and lesioned OE were examined for the number of β-galactosidase+ (β-gal+) neuronal clusters (clusters), the cellular composition of individual clusters (cluster composition), and the total number of β-gal+ cells (total cells). In parentheses is shown the range of each data set.
Abbreviations: GBC, globose basal cell; OE, olfactory epithelium; ORN, olfactory receptor neuron; SUS, sustentacular cell.