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. 2014 Jul 10;9(7):e101249. doi: 10.1371/journal.pone.0101249

Table 4. Usefulness of both IEL flow cytometric pattern and IF pattern for the diagnosis of CD in patients with lymphocytic enteritis (Marsh 1 type lesion).

Parameter Serum anti-TG2+ Serum anti-TG2− Overall
‘Gold standard’+n = 12 ‘Gold standard’+n = 8 ‘ProbableCD’ n = 7* ‘Non-celiac’n = 43 ‘Gold standard’+n = 20
Complete FCP 9 4 7 0 13 (65%)**
Incomplete FCP 3 3 0 2 6 (30%)**
IF pattern 8 4+ 1 3 12 (60%)
Incomplete/IF pattern 1 2 0 0 3 (15%)

FCP: Flow cytometric pattern.

*A GFD could not be started in 3 patients (1 not accepted, 2 non-symptomatic first degree relatives); Response to a GFD not evaluable in 4 patients (2 lost in follow-up, 2 with associated psychiatric disorders).

+

1 patient with an isolated CD IF pattern at inclusion developed positive EmA and the complete CD cytometric pattern in a follow-up duodenal biopsy.

**Positive FCP (65%+30% = 95%) vs positive IF pattern (60%), p = 0.039 (McNemar Test).