Table 3.
Table 3a. Genes differentially expressed in two or more unselected FS0 strains relative to the New Orleans strain. Ratio of the average expression of each comparison is displayed on a linear scale. Probability value is shown as a negative log10 scale. | |||||||||||
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Activity Gene | Vector Base ID | Iquitos | Calderitas | Lázaro-Cárdenas | Lagunitas | Mérida | |||||
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Ratio | p | Ratio | p | Ratio | p | Ratio | p | Ratio | p | ||
GSTs | |||||||||||
GSTd1-1 | AAEL001061 | 2.78 | 20.84 | 0.44 | 12.38 | ||||||
GSTd1-2 | AAEL001061 | 2.70 | 5.43 | 4.17 | 5.50 | 2.26 | 7.71 | ||||
GSTe2 | AAEL007951 | 5.59 | 16.69 | 2.70 | 5.21 | 4.87 | 23.92 | ||||
GSTe3 | AAEL007947 | 2.68 | 7.41 | 7.07 | 14.86 | 7.18 | 16.83 | 8.77 | 9.94 | 5.87 | 20.36 |
GSTe4 | AAEL007962 | 4.58 | 15.85 | 3.09 | 9.63 | 3.29 | 23.43 | ||||
GSTe6 | AAEL007946 | 4.24 | 15.69 | 4.90 | 12.78 | 4.48 | 19.22 | ||||
GSTe7 | AAEL007948 | 3.10 | 15.66 | 4.09 | 20.06 | 4.13 | 7.57 | 2.21 | 18.68 | ||
GSTs1-2 | AAEL011741 | 0.48 | 4.57 | 0.34 | 8.52 | 0.48 | 12.20 | ||||
CYPs | |||||||||||
CYP6F3 | AAEL014684 | 2.76 | 16.69 | 3.36 | 13.40 | ||||||
CYP4H28 | AAEL003380 | 0.27 | 14.55 | 0.18 | 18.48 | 0.19 | 21.21 | ||||
CYP4J15 | AAEL013556 | 2.10 | 11.22 | 2.63 | 9.29 | 2.44 | 16.91 | ||||
CYP6N11 | AAEL009138 | 0.34 | 10.29 | 0.38 | 14.14 | ||||||
CYP6P12 | AAEL014891 | 0.43 | 5.90 | 0.49 | 11.17 | ||||||
CYP6Z8 | AAEL009131 | 2.20 | 16.89 | 2.33 | 12.16 | 2.75 | 24.41 | ||||
CYP9AE1 | AAEL003748 | 0.44 | 7.96 | 0.39 | 5.16 | ||||||
CYP9M9 | AAEL001807 | 5.49 | 17.45 | 3.53 | 9.12 | 9.25 | 22.49 | ||||
CYP9J15 | AAEL006795 | 0.48 | 16.71 | 0.35 | 14.14 | ||||||
CYP9J19 | AAEL006810 | 2.23 | 10.20 | 2.19 | 7.92 | 3.77 | 16.84 | ||||
CYP9J24 | AAEL014613 | 2.02 | 11.01 | 2.20 | 4.95 | ||||||
CYP9J26 | AAEL014609 | 2.23 | 19.84 | 2.33 | 9.23 | 2.43 | 6.97 | 2.34 | 4.42 | ||
CYP9J32 | AAEL008638 | 6.86 | 18.56 | 2.15 | 14.08 | 2.79 | 7.19 | 2.50 | 22.52 | ||
CCEs | |||||||||||
COE-1 | AAEL003201 | 0.25 | 5.83 | 4.26 | 8.00 | 2.32 | 19.83 | ||||
COE-2 | AAEL002376 | 2.70 | 16.62 | 2.41 | 16.79 | ||||||
COE-19 | AAEL005112 | 2.87 | 18.63 | 2.30 | 13.54 | ||||||
CCae1C | AAEL003195 | 0.22 | 8.52 | 2.08 | 13.37 | 3.74 | 10.99 | 2.95 | 18.09 | ||
CCae2C | AAEL003196 | 0.33 | 7.84 | 2.87 | 15.50 | 3.88 | 11.86 | 2.97 | 20.21 | ||
CCae3o | AAEL011944 | 0.30 | 13.81 | 3.23 | 11.17 | ||||||
CCae4C | AAEL003187 | 0.25 | 13.80 | 0.17 | 14.87 | 0.22 | 18.30 | 0.21 | 16.86 | ||
CCae5C | AAEL003201 | 0.13 | 13.84 | 4.00 | 11.74 | ||||||
CCae6C | AAEL003198 | 3.30 | 10.38 | 2.30 | 19.72 | ||||||
CCEjhe2o | AAEL004323 | 0.42 | 11.86 | 0.34 | 12.00 | ||||||
RedOx | |||||||||||
Glutathione peroxidase 495 | AAEL000495 | 2.23 | 13.28 | 2.57 | 19.20 | ||||||
Superoxide Dismutase (Cu-Zn) | AAEL006271 | 0.43 | 13.07 | 0.18 | 10.93 | 0.14 | 13.99 | ||||
AAGE1005255 | AAGE1005255 | 0.44 | 17.09 | 0.44 | 16.31 | ||||||
Heme peroxidase 6014 | AAEL006014 | 9.03 | 15.40 | 5.24 | 11.31 | 0.49 | 14.18 | ||||
Thioredoxin peroxidase 4112 | AAEL004112 | 0.44 | 5.47 | 0.38 | 12.71 | ||||||
Thioredoxin peroxidase 2309 | AAEL002309 | 0.39 | 9.50 | 0.41 | 8.01 | ||||||
Catalase | AAEL013407 | 0.38 | 12.69 | 2.10 | 13.79 |
Table 3b. Genes differentially expressed in one of the unselected FS0 strains relative to the susceptible New Orleans strain | |||||||||||
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GSTs | |||||||||||
AaGSTd1-3 | AAEL001061 | 2.07 | 15.87 | ||||||||
AaGSTu2 | AAEL000092 | 0.36 | 13.98 | ||||||||
CYPs | |||||||||||
CYP304C1 | AAEL014413 | 0.44 | 7.54 | ||||||||
CYP325AA1 | AAEL004012 | 2.07 | 8.33 | ||||||||
CYP325E3 | AAEL000338 | 0.43 | 3.70 | ||||||||
CYP325X2 | AAEL005696 | 3.23 | 16.33 | ||||||||
CYP4D23 | AAEL007816 | 2.5 | 18.47 | ||||||||
CYP4G36 | AAEL004054 | 0.43 | 10.41 | ||||||||
CYP4H31 | AAEL002085 | 0.41 | 4.36 | ||||||||
CYP4J14 | AAEL013554 | 2.72 | 19.68 | ||||||||
CYP6AG7 | AAEL006989 | 2.68 | 20.85 | ||||||||
CYP6BB | AAEL014893 | 3.04 | 9.64 | ||||||||
CYP6F2 | AAEL014678 | 0.48 | 16.28 | ||||||||
CYP6N16 | AAEL010151 | 0.41 | 17.09 | ||||||||
CYP6N6 | AAEL009126 | 2.09 | 3.44 | ||||||||
CYP6Y3 | AAEL009132 | 2.31 | 17.92 | ||||||||
CYP6Z9 | AAEL009129 | 0.40 | 8.71 | ||||||||
CYP9J10 | AAEL014614 | 2.00 | 16.21 | ||||||||
CYP9J20 | AAEL006814 | 2.60 | 8.68 | ||||||||
CYP9J22 | AAEL006802 | 2.71 | 16.15 | ||||||||
CYP9J8 | AAEL014608 | 0.46 | 7.83 | ||||||||
AAGE01273771 | AAEL009124 | 2.20 | 12.25 | ||||||||
CCEs | |||||||||||
COE-17 | AAEL004341 | 0.33 | 9.15 | ||||||||
COE-6 | AAEL005200 | 2.54 | 8.91 | ||||||||
RedOx | |||||||||||
Peroxidasin 376 | AAEL000376 | 2.12 | 14.19 | ||||||||
Peroxinectin 3612 | AAEL003612 | 0.39 | 5.61 | ||||||||
Peroxinectin 4386 | AAEL004386 | 0.49 | 4.46 | ||||||||
Peroxinectin 4388 | AAEL004388 | 0.33 | 7.52 | ||||||||
Peroxinectin 4390 | AAEL004390 | 0.29 | 5.51 | ||||||||
Peroxinectin 4400 | AAEL004400 | 0.37 | 5.53 | ||||||||
Ubiquinol-cytochrome c reductase | AAEL007868 | 0.48 | 17.80 | ||||||||
Oxidase/peroxidase 13171 | AAEL013171 | 0.47 | 7.83 | ||||||||
Thioredoxin peroxidase 13528 | AAEL013528 | 0.43 | 19.04 | ||||||||
Thioredoxin 9351 | AAEL009351 | 0.46 | 13.99 | ||||||||
Misc. | |||||||||||
60S ribosomal protein L44 | AAEL003942 | 0.48 | 11.65 | ||||||||
Ribosomal S17 | AAEL004175 | 0.45 | 16.69 |