Table 1.
Gene expression profile of THP-1 treated with JTT
| UniGene ID | Gene | Fold Change | Log ratio a | Change p-value b |
|---|---|---|---|---|
| Hs.75703 | CCL4 chemokine | 89.0 | 6.5 | 0.00006 |
| Hs.437322 | TNF-α induced protein 6 | 74.8 | 6.2 | 0.00002 |
| Hs.632586 | CXCL10 chemokine | 54.8 | 5.8 | 0.00002 |
| Hs.450230 | IGF binding protein 3 | 26.9 | 4.8 | 0.00040 |
| Hs.574492 | Nucleoporin | 26.0 | 4.7 | 0.00017 |
| Hs.137459 | Shroom family 3 | 23.4 | 4.6 | 0.00075 |
| Hs.31210 | BCL3 | 17.8 | 4.2 | 0.00009 |
| Hs.514107 | CCL3 chemokine | 17.4 | 4.1 | 0.00003 |
| Hs.126256 | Interleukin 1β (IL1B) | 16.0 | 4.0 | 0.00035 |
| Hs.624 | Interleukin 8 (IL8) | 14.9 | 3.9 | 0.00003 |
| Hs.632592 | CXCL11 chemokine | 14.2 | 3.8 | 0.00070 |
| Hs.241570 | TNF | 13.5 | 3.8 | 0.00007 |
| Hs.643447 | ICAM-1 | 11.9 | 3.6 | 0.00033 |
| Hs.591338 | TNF-α induced protein 3 | 11.5 | 3.5 | 0.00002 |
The expression profiling was carried out with Affymetrix Human Genome U133 Plus 2.0 array.
a
Log Ratio is log2(signal of JTT-treated cells/signal of control cells).
b
Change p-values were calculated using the Wilcoxon signed rank test and Tukey Biweight on the Affymetrix Microarray Suite Version 5.0 (MAS5) Software.