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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Psychopharmacology (Berl). 2013 Jul 5;230(3):375–387. doi: 10.1007/s00213-013-3164-z

Table 1.

Frequency of aggressive behaviors after microinjection of vehicle, F15599 (5-HT1A receptor agonist, in different doses) and WAY100, 635 (5-HT1A receptor antagonist (before F15599 or vehicle)) in the ventral orbital (VO) prefrontal cortex (PFC)

Vehicle F15599 doses (μg/0.2 μl)
Vehicle + WAY100,635 1.0 μg +
Behavior 0.2 μl (n=10) 0.03 (n=8) 0.1 (n=10) 0.3 (n=6) 1.0 (n=10) Vehicle 0.2 μl (n=6) F15599 0.1 μg (n=6) Vehicle 0.2 μl (n=7)
Frequency of aggressive elements
 Pursuit 0.4 ± 0.2 0.6 ± 0.3 0.1 ± 0.1 0.7 ± 0.7 1.0 ± 0.7 1.3 ± 0.6 0.5 ± 0.3 1.0 ± 0.5
 Sniff 5.4 ± 1.2 6.4 ± 1.5 9.5 ± 2.3 11.2 ± 2.1 8.1 ± 1.8 11.0 ± 2.2 13.5 ± 1.6 12.1 ± 1.7
 Tail rattle 25.0 ± 3.5 13.5 ± 2.0 15.8 ± 4.2 17.2 ± 3.0 24.0 ± 6.3 15.2 ± 2.4 12.7 ± 4.0 17.6 ± 2.9

Data expressed in mean ± SEM