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. Author manuscript; available in PMC: 2014 Jul 10.
Published in final edited form as: Cell Transplant. 2012;21(7):1419–1430. doi: 10.3727/096368911X627480

Figure 6. ActRIIB/Fc treatments increased the number of lamin A/C nuclei in individual dystrophin positive fiber and induced hypertrophy of the dystrophin positive fibers.

Figure 6

(a) Repartition of dystrophin positive fibers based on the number of lamin A/C nuclei inside their cross-section in the no swimming groups treated or not with ActRIIB/Fc (2 injections/week). (b) Repartition of dystrophin positive fibers based on the number of lamin A/C nuclei inside their cross-section in the weekly swimming groups treated or not with ActRIIB/Fc (5 injections/week). (c) Cross-sectional area of human-dystrophin positive myofibers, measured in the TAs of Rag−/− mdx mice treated or not with ActRIIB/Fc and forced or not to swim. The means are represented (+ SD, N=6). * p<0.05