Skip to main content
. Author manuscript; available in PMC: 2014 Jul 10.
Published in final edited form as: Compr Physiol. 2013 Jul;3(3):1035–1078. doi: 10.1002/cphy.c120027

Figure 4.

Figure 4

Graphic representation of determinants of bile flow. Top: canalicular bile flow consists of a bile salt-dependent (BSDF) and a bile salt-independent (BSIF) fraction. The BSDF increases linearly as a function of bile salt excretion. Both canalicular bile flow and secretion from the bile ducts contribute to total bile flow. Bottom: choleretic potential varies among bile salts. Bile flow is linearly related to bile salt excretion, but hypercholeretic bile salts increase bile flow more rapidly than do bile salts with normal choleretic potential. Reprinted, with permission, from Ref. (76).