Figure 6. H. polygyrus-infection induces the inhibition of LPS-, but not IL-1β-, induced pro-inflammatory cytokine production.

The peritoneal macrophages were collected from normal and helminth-infected mice and re-stimulated the cells in vitro with LPS (100 ng/ml) or IL-1β (1 ng/ml) for 1 or 6 h. Culture supernatants were collected (at 6 h). TNF-α (A) and IL-6 (B) production was measured by Cytokine ELISA. KC expression (C) (at 1 h) was determined by Real time RT-PCR. *p<0.05, n = 5–10 mice per group.