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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Bone. 2014 May 15;65:83–91. doi: 10.1016/j.bone.2014.05.006

Figure 3.

Figure 3

a) MS/BS+, (b) MAR+, (c) BFR/BS+ and (d) incidence of woven bone (number of mice per group showing load-induced woven bone) of the periosteal and endocortical envelopes from a range of adult tibiae (only right tibiae) subjected to compression at –2200 με and –3000 με. Aging reduced the periosteal bone formation by tibial compression at –2200 με with minimal differences in bone formation outcomes between middle-aged and old tibiae and no endocortical changes between ages. Loading at –3000 με induced similar changes but enhanced periosteal bone formation of 5-month tibiae by inducing woven bone. Data are represented as mean±SD. Black bracket: significant difference between ages; “a”: significant difference between loading magnitudes of respective age. +: Represents the combination of woven and lamellar values; p<0.05.