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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Bone. 2014 May 15;65:83–91. doi: 10.1016/j.bone.2014.05.006

Table 2.

Structural morphology of varying aged cortical bone subjected to two tibial compression loading magnitudes

Outcomes Time
[weeks]
−2200 με −3000 με
5 mo (n=13) 12 mo (n=12) 22 mo (n=12) 5 mo (n=15) 12 mo (n=15) 22 mo (n=14)
Control Loaded Control Loaded Control Loaded Control Loaded Control Loaded Control Loaded
Ct.BV [mm3] 0 week 0.94 ± 0.05 0.91 ± 0.06 0.89 ± 0.09 0.87 ± 0.10 0.74 ± 0.07 0.71 ± 0.04 0.95 ± 0.05 0.94 ± 0.04 0.87 ± 0.06 0.85 ± 0.06 0.78 ± 0.14 0.74 ± 0.06
2 weeks 0.90 ± 0.05* 0.95 ± 0.07 0.84 ± 0.10* 0.85 ± 0.11 0.70 ± 0.09* 0.70 ± 0.06 0.91 ± 0.05* 1.10 ± 0.08* 0.82 ± 0.05* 0.90 ± 0.08* 0.71 ± 0.08* 0.80 ± 0.09*
Ct.TV [mm3] 0 week 1.38 ± 0.10 1.34 ± 0.12 1.41 ± 0.12 1.37 ± 0.12 1.41 ± 0.10 1.41 ± 0.07 1.47 ± 0.09 1.46 ± 0.09 1.42 ± 0.12 1.42 ± 0.11 1.52 ± 0.24 1.49 ± 0.12
2 weeks 1.36 ± 0.12 1.48 ± 0.16* 1.43 ± 0.13 1.42 ± 0.13* 1.41 ± 0.09 1.45 ± 0.10* 1.45 ± 0.07 1.70 ± 0.08* 1.42 ± 0.09 1.55 ± 0.12* 1.51 ± 0.15 1.63 ± 0.09*
Me.V [mm3] 0 week 0.44 ± 0.06 0.43 ± 0.07 0.52 ± 0.11 0.49 ± 0.11 0.67 ± 0.06 0.70 ± 0.07 0.52 ± 0.05 0.52 ± 0.05 0.55 ± 0.07 0.57 ± 0.08 0.75 ± 0.12 0.75 ± 0.09
2 weeks 0.46 ± 0.07 0.53 ± 0.10* 0.58 ± 0.14* 0.57 ± 0.13* 0.71 ± 0.07 0.75 ± 0.08* 0.54 ± 0.03 0.60 ± 0.06* 0.59 ± 0.05* 0.65 ± 0.09* 0.80 ± 0.11* 0.83 ± 0.11*
TMD [mg HA/cm3] 0 week 1054 ± 22 1057 ± 13 1079 ± 28 1074 ± 28 1048 ± 61 1065 ± 27 1050 ± 16 1056 ± 13 1079 ± 22 1088 ± 15 1035 ± 30 1069 ± 22
2 weeks 1041 ± 29* 1059 ± 13 1066 ± 26 1078 ± 19 1031 ± 50 1068 ± 26 1044 ± 25 1066 ± 12* 1074 ± 22 1098 ± 16* 1031 ± 35 1076 ± 19
*

p<0.05, 0 week vs. 2 weeks