Fig. 1.

Bioinformatic prediction of conserved chemerin-derived peptide C-20. Amino acid sequences of pre-pro-chemerin from different vertebrates are aligned to search for evolutionary conserved putative peptide regions. Consensus basic residues representing putative convertase cleavage sites are shadowed and indicated by arrows, flanking the predicted chemerin-derived-peptide C-20. GenBank numbers for individual chemerin genes are human: NP_002880.1; chimpanzee: JAA28993.1; monkey: NP_001253612.1; rabbit: XP_002722563.1; pig: NP_001116658.1; cattle: NP_001039485.1; rat: NP_001013445.1; hamster: NP_001231216.1; mouse: NP_082128.1.