C-20 elicited chemotactic response of huCMKLR1/L1.2 cells. HuChemerin stimulated the chemotaxis of huCMKLR1/L1.2 cells at 0.3, 1, 10 nm concentration, while the dose of 100 nm showed no effect. HuC-20 showed no chemotaxis effect at 0.3 nm, while effective at 1, 10, and 100 nm. The optimal dose of chemotaxis for huChemerin was 1 nm compared with the 10 nm of huC-20. WT/L1.2 cells showed no chemotactic response. *P < 0.05 compared with control group with culture media only, by one-way anova followed by Student-Newman-Keuls test.