. 2014 Jan 10;29(12):2273–2287. doi: 10.1007/s00467-013-2677-3

Table 3.

Pathogen/microbial-associated molecular patterns (P/MAMP) and corresponding human Toll-like receptors (TLRs) and microbial source (pathogen)

P/MAMP	PRR	Pathogen
Peptidoglycan, Pam3CSK4^a, Zymosan	TLR1 TLR2 TLR6^b	Gram-positive bacteria
dsRNA	TLR3	Virus
LPS, Lipid A	TLR4	Gram-negative bacteria
Flagellin	TLR5	Bacteria, Flagellum
ssRNA	TLR7 TLR8	Virus
CpG DNA motifs	TLR9	Bacteria, DNA
Profilin-like proteins	TLR10

PRR, pattern recognition receptors

^aSynthetic triacylated lipopeptide

^bHeterodimerizes with TLR1, TLR2