Table 2. Association analysis of genetic variants in DNA repair genes with the risk of major NHL subtypes.

						DLBCL		FL		SLL/CLL
						(412 Cases/1,946 Controls)		(301 Cases/1,946 Controls)		(164 Cases/1,946 Controls)
Gene	Chr.	SNP	Minor Allele	Allele Freq.		OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	Breslow-Day P
ATM	11	rs611646	T	0.45		1.37 (1.14–1.64)	7.7×10−4	1.19 (0.96–1.46)	0.108	1.41 (1.06–1.87)	0.017	0.132
ATM	11	rs227060	T	0.37		1.34 (1.13–1.58)	8.7×10−4	1.10 (0.91–1.34)	0.334	1.58 (1.21–2.06)	6.7×10−4	0.037
ATM	11	rs419716	T	0.42		0.75 (0.62–0.90)	0.0026	0.84 (0.68–1.04)	0.107	0.84 (0.63–1.11)	0.217	0.229
MRE11A	11	rs10831227	A	0.34		0.77 (0.65–0.93)	0.0050	0.91 (0.75–1.11)	0.361	0.97 (0.74–1.26)	0.803	0.479
ATR	3	rs10804682	A	0.20		1.27 (1.05–1.55)	0.016	1.09 (0.86–1.37)	0.480	1.17 (0.87–1.59)	0.296	0.152
POLQ	3	rs702019	G	0.23		0.79 (0.64–0.97)	0.025	0.81 (0.64–1.03)	0.082	0.98 (0.71–1.34)	0.876	0.362
NBS1	8	rs14448	C	0.06		1.39 (1.01–1.93)	0.047	1.11 (0.74–1.65)	0.625	0.87 (0.48–1.58)	0.654	0.320
MSH2	2	rs4952887	T	0.07		0.72 (0.52–1.00)	0.048	0.71 (0.49–1.03)	0.073	0.63 (0.38–1.06)	0.079	0.432
CCNH	5	rs3093819	T	0.46		1.15 (0.98–1.37)	0.095	1.29 (1.06–1.57)	0.012	1.14 (0.87–1.49)	0.341	0.773
MRE11A	11	rs625245	C	0.32		0.85 (0.71–1.03)	0.106	0.78 (0.63–0.97)	0.028	0.87 (0.65–1.16)	0.347	0.810
GTF2H1	11	rs4150606	A	0.50		0.88 (0.74–1.05)	0.144	0.84 (0.69–1.02)	0.083	0.52 (0.39–0.69)	4.8×10−6	0.001
CHEK1	11	rs565416	A	0.32		0.97 (0.82–1.16)	0.749	0.71 (0.58–0.87)	0.0012	0.99 (0.76–1.28)	0.915	0.006
TDP1	14	rs7149962	C	0.06		1.06 (0.73–1.52)	0.773	1.64 (1.14–2.35)	0.0076	0.91 (0.52–1.60)	0.754	0.921
NBS1	8	rs1805812	C	0.06		0.68 (0.45–1.04)	0.073	0.72 (0.46–1.15)	0.168	1.05 (0.58–1.88)	0.877	0.831
MSH6	2	rs7562048	G	0.44		0.87 (0.73–1.05)	0.146	0.87 (0.71–1.06)	0.162	0.84 (0.64–1.09)	0.188	0.150

DLBCL = diffuse large B-cell lymphoma; FL = follicular lymphoma; SLL/CLL = small lymphocytic lymphoma/chronic lymphocytic leukemia; OR = odds ratio; CI = confidence interval.