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. 2014 Jul 10;9(7):e102190. doi: 10.1371/journal.pone.0102190

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© 2014 Spencer et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Cell size from Figure 1B was measured in all adipocytes from a whole slide scan, representing 8000–12000 cells, and the distribution of cell cross-sectional area relative frequency is shown before and after pioglitazone treatment. B. Average adipocytes cross-sectional area. C. Analysis of images illustrated in Figure 1D for overall collagen. D. Analysis of images illustrated in Figure 1C for elastin. *p<0.05 vs pre-pioglitazone.