Table 1.
Description of Cohort Demographics and Arrest Characteristics and the Association of Cardiac Arrest Variables With Mortality
| Survival Outcome (n = 264)
|
p | |||
|---|---|---|---|---|
| Total (n = 264), n (%) or Median (Interquartile Range) | Nonsurvivors (n = 138), n (%) | Survivors (n = 126), n (%) | ||
| Age (mo) | 13 (2, 96) | 16 (2, 130) | 9 (2, 73) | 0.09 |
|
| ||||
| Gender | 0.75 | |||
| Male | 161 (61) | 82 (51) | 79 (49) | |
| Female | 100 (38) | 53 (53) | 47 (47) | |
| Unknown | 3 (1) | 3 (100) | 0 (0) | |
|
| ||||
| Race | 0.82 | |||
| Black | 124 (47) | 32 (49) | 33 (51) | |
| White | 65 (25) | 67 (54) | 57 (46) | |
| Other/unknown | 75 (28) | 39 (52) | 36 (48) | |
|
| ||||
| Preexisting condition | ||||
| Prenatal | 31 (12) | 16 (52) | 15 (48) | 0.94 |
| Lung or airway | 67 (25) | 28 (42) | 39 (58) | 0.047 |
| Congenital heart disease | 113 (43) | 53 (47) | 60 (53) | 0.13 |
| Acquired heart disease | 27 (10) | 14 (52) | 13 (48) | 0.96 |
| Hematology/oncology/immunology | 30 (11) | 20 (67) | 10 (33) | 0.09 |
| Gastrointestinal | 39 (15) | 21 (54) | 18 (46) | 0.83 |
| Genetic/metabolic | 31 (12) | 21 (68) | 10 (32) | 0.07 |
| Endocrine | 6 (2) | 5 (83) | 1 (17) | 0.22 |
| Renal | 24 (9) | 17 (71) | 7 (29) | 0.056 |
| Neurologic | 62 (24) | 30 (48) | 32 (52) | 0.48 |
|
| ||||
| Initial rhythm | 0.013 | |||
| Asystole/pulseless electrical activity | 76 (29) | 49 (64) | 27 (36) | |
| Ventricular fibrillation/pulseless ventricular tachycardia | 30 (11) | 15 (50) | 15 (50) | |
| Bradycardia | 111 (42) | 46 (41) | 65 (59) | |
| Other/unknown | 47 (18) | 28 (60) | 19 (40) | |
|
| ||||
| Cardiopulmonary resuscitation (min) | 14 (5, 35) | 19 (6, 47) | 8 (3, 20) | < 0.001 |
|
| ||||
| Epinephrine doses | < 0.001 | |||
| 0 | 36 (14) | 14 (39) | 22 (61) | |
| 1 | 61 (23) | 24 (39) | 37 (61) | |
| 2 | 44 (17) | 19 (43) | 25 (57) | |
| 3 | 45 (17) | 26 (58) | 19 (42) | |
| ≥ 4 | 68 (26) | 49 (72) | 19 (28) | |
| Unknown | 10 (4) | 6 (60) | 4 (40) | |
|
| ||||
| Witnessed | 0.37 | |||
| Yes | 25 | 14 (56) | 11 (44) | |
| No | 31 | 21 (68) | 10 (32) | |
|
| ||||
| Location | 0.047 | |||
| In hospital | 206 (78) | 101 (49) | 105 (51) | |
| Out of hospital | 58 (22) | 37 (64) | 21 (36) | |
|
| ||||
| Number of vasoactives 0–6 hr | 0.29 | |||
| 0 | 47 (18) | 21 (15) | 26 (21) | |
| 1 | 66 (25) | 31 (22) | 35 (28) | |
| 2 | 80 (30) | 48 (35) | 32 (25) | |
| ≥ 3 | 71 (27) | 38 (28) | 33 (26) | |
|
| ||||
| Minimum pH 0–6 | 7.20 (7.00, 7.33) | 7.09 (6.88, 7.28) | 7.28 (7.14, 7.37) | < 0.001 |
|
| ||||
| Minimum pH 7–12 | 7.37 (7.27, 7.45) | 7.31 (7.20, 7.42) | 7.40 (7.35, 7.46) | < 0.001 |
|
| ||||
| Maximum lactate 0–6 | 8.2 (3.3, 14.1) | 11.9 (6.4, 18.1) | 5.3 (2.2, 10) | < 0.001 |
|
| ||||
| Maximum lactate 7–12a | 4.7 (2, 10.7) | 8.8 (3.8, 15.9) | 2.7 (1.6, 5.7) | < 0.001 |
Age and lactate variables are represented as median (interquartile range) Each patient can have more than one preexisting condition.
a
n = 153.