Table 1.
Transcriptomic metadata of chick myogenic cells
| Transcriptome control | MbCD-treated transcriptome | ||
|---|---|---|---|
| MG-RASTID | 4512803.3 | 4512804.3 | |
| Transcriptome Size (post QC) (Mbp) | 337.68 | 333.70 | |
| Average size (post QC) (bp) | 115 ± 62 | 117 ± 58 | |
| Total number of sequences (post QC) | 2,926,445 | 2,851,594 | |
| Classification COG | 499,559 (17.07%) | 622,533 (21.83%) | |
| Control | MbCD | Total | |
| Different categories identifiable (COG) | 3,625 | 4,160 | 4,415 |
| Statistically different functions | n.a. | n.a. | 1,408(31.89%)1 |
| Up-regulation with MbCD treatment | n.a. | 785(55.75%)2 | n.a. |
| Down-regulation with MbCD treatment | 623 (44.25%)2 | n.a. | n.a. |
n.a. not applicable, 1percentage of total different categories, 2percentage of statistically different functions.
From a total of 4,415 identified transcripts, 1,408 (31.89%) had their transcription significantly modified. Among these, 785 genes were up-regulated and 623 were down-regulated after cholesterol depletion.