Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 11;5:252. doi: 10.3389/fphys.2014.00252

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Lu, Zhang, Zhang, Yang, Wu, Xie, Luan and Ling.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Comparison of the amino acid sequences of Homo sapiens tyrosinase (HsTyrosinase; Accession number: AAB60319) and Bacillus megaterim tyrosinase (BmTyrosinase; Accession number: ACC86108). The online CLUSTALW multiple sequence alignment software (http://www.genome.jp/tools/clustalw/) was used for the slow and accurate pairwise alignment analysis. “^*,” Fully conserved residues; “:,” conserved substitutions; “.,” semi-conserved substitution as previously described (Grasela et al., 2008). Copper-binding regions A and B are underlined. The histidine residues marked with “▲” are the ligands proposed to coordinate two copper ions in the active site pocket.