Table 1.

Examples of compounds that activated all three receptors with TRPA1V1 showing differential modulation.

Compound	TRPA1	TRPA1V1	TRPV1	Remarks
Ethyl 3-hydroxyoctanoate	97.29	76.90	28.05	Negative effect of V1
Geraniol	82.52	63.93	42.16	Negative effect of V1
5-Oxodecanoic acid	28.57	39.34	53.38	Negative effect of A1
Vanillylacetone	22.26	37.75	60.05	Negative effect of A1
2-Napphlaenthiol	66.3	85.2	120.3	Negative effect of A1
3-Methyl-5-propyl-2-cyclohexen-1-one	69.00	101.0	59.22	A1 and V1 additive
Benzaldehyde propylene glycol acetal	48.03	78.33	34.38	A1 and V1 additive
Methyl cyclohexanecarboxylate	45.50	85.17	69.51	A1 and V1 additive
4-Hydroxybenzaldehyde	80.4	163.2	123.1	A1 and V1 additive