. 2014 May 6;3(2):386–417. doi: 10.3390/cells3020386

Table 2.

A list of viral proteins with recognized deubiquitinating enzyme (DUB) activity is reported along with the characterized substrates.

Virus	Viral protein	Target protein	Reference
Herpes simplex virus type 1	UL36	TRAF3	Wang et al. 2013 [100]
Herpes simplex virus type 1	UL36	UL36 (viral)	Bolstad et al. 2011 [101]
Human cytomegalovirus	UL48	unknown	Kim et al. 2009 [102]
PseudoRabies Virus	UL36	unknown	Bottcher et al. 2008 [103]
Kaposi Sarcoma-associated herpesvirus	ORF64	RIG-I	Inn et al. 2011 [104]
Kaposi Sarcoma-associated herpesvirus	RTA	IRF-7	Isaacson et al. 2009 [80]
Epstein-Barr Virus	BPLF1	EBV ribonucleotide reductase (viral)	Whitehurst et al. 2009 [97]
		PCNA	Kumar et al. 2014 [99]
		Rad18	Kumar et al. 2014 [99]
Crimean-Congo Hemorrhagic Fever Virus	vOTU	Unknown	Akutsu et al. 2011 [105]
Marek's Disease Virus	UL36	Unknown	Isaacson et al. 2009 [80]
Human coronavirus	PLpro	Unknown	Mielech et al. 2014 [106]
Turnip Yellow Mosaic Virus	PRO	Unknown	Lombardi et al. 2013 [107]
Turnip Yellow Mosaic Virus	98K	RdRp (viral)	Chenon et al. 2012 [108]
Porcine Epidemic Diarrhea Virus	PLP2	RIG-I	Xing et al. 2013 [109]
Porcine Epidemic Diarrhea Virus	PLP2	STING	Xing et al. 2013 [109]
Porcine Reproductive and Respiratory Syndrome Virus	nsp2	IkBα	Sun et al. 2010 [110]
Adenovirus	Avp	Adenoviral and cellular proteins unknown	Balakirev et al. 2002 [111]