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Checkpoint pathway, in response to DNA damage, that leads to growth arrest at the G2/M interphase of the cell cycle in epithelioid cells. The inset illustrates the standard DNA damage checkpoints at G1/S and G2/M in the cell cycle. Cell cycle arrest at G2/M can be measured by flow cytometry or cell sorting. Populations that are arrested at G2/M accumulate cells that have a 4n DNA content.
