Skip to main content
. 2014 May 20;3(2):438–454. doi: 10.3390/cells3020438

Figure 1.

Figure 1

Functional domains and sites in ICP0 relevant to this review. The T67 phosphorylation site, RING-finger motif, ICP0 phosphorylation (Phos) region I (amino acids 224–232), nuclear localization signal (NLS), USP7 binding site, ND10 localization domain, and SIMs (SUMO interaction motifs) 1–7, which start at amino acids 162, 174, 331, 360, 650, 665, and 679 of ICP0, respectively [22].