Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr 29;3(2):363–385. doi: 10.3390/cells3020363

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

PMC Copyright notice

Effects of Rab silencing on VEGF-A-stimulated intracellular signalling in endothelial cells. (A) HUVECs were subjected to RNAi (see Materials and Methods) and the control; Rab4a- or Rab11a-depleted HUVECs were then stimulated with VEGF-A followed by quantitative immunoblotting for (B) VEGFR2-pY1175, (C) phosphorylated Akt (p-Akt S473), (D) phosphorylated MAPK (p42/44 MAPK or p-ERK1/2 T202/Y204) and (E) phosphorylated eNOS (p-eNOS S1179). The data shown are derived from the analysis of three or more independent experiments. Error bars denote ±SEM, with asterisks indicating significance (*, p < 0.05).