Table 1.
PC | CHR | SNP | Position | Minor/major | MAFa | BETAb | p-value | Nearby gene | Typec |
---|---|---|---|---|---|---|---|---|---|
PC1 | 2 | ASGA0010593 | 85596454 | G/A | 0.425 | 0.013 | 5.56E-06 | SNORA70 | 7365 |
2 | MARC0001645 | 87106234 | A/G | 0.384 | 0.015 | 1.35E-06 | ENSSSCG00000014087 | Genic | |
2 | UMB10000069 | 87305603 | G/A | 0.365 | 0.015 | 7.70E-07 * | ENSSSCG00000025645 | Genic | |
2 | M1GA0002981 | 87507128 | A/G | 0.392 | 0.014 | 4.58E-06 | AGGF1 | Genic | |
2 | MARC0023062 | 87571413 | G/A | 0.394 | 0.014 | 6.26E-06 | SNORA47 | −2363 | |
2 | ASGA0010696 | 87821516 | G/A | 0.403 | 0.014 | 4.45E-06 | PDE8B | Genic | |
17 | INRA0052583 | 12436823 | A/G | 0.428 | 0.013 | 5.48E-06 | ANK1 | −17485 | |
17 | ASGA0075294 | 12781032 | A/G | 0.483 | −0.013 | 6.99E-07* | C8ORF40 | 31476 | |
17 | ASGA0075297 | 12798139 | G/A | 0.431 | −0.016 | 6.92E-08* | C8ORF40 | 14369 | |
17 | DIAS0003526 | 12823893 | G/A | 0.431 | −0.016 | 6.92E-08* | C8ORF40 | Genic | |
17 | ALGA0093121 | 12877758 | A/G | 0.392 | −0.016 | 5.24E-08* | C8ORF40 | −53786 | |
17 | ASGA0075278 | 12896953 | C/A | 0.326 | −0.016 | 2.04E-07* | ENSSSCG00000007025 | 45324 | |
17 | ASGA0075277 | 13015930 | G/A | 0.392 | −0.016 | 5.24E-08* | SLC20A2 | Genic | |
PC2 | 7 | ASGA0030822 | 5278629 | C/A | 0.328 | −0.015 | 1.09E-06* | BMP6 | Genic |
8 | ASGA0093827 | 76550202 | A/G | 0.086 | −0.021 | 1.09E-06* | SHROOM3 | Genic | |
9 | ASGA0095397 | 17376220 | A/G | 0.108 | −0.021 | 1.20E-06 | ENSSSCG00000014896 | −88,4312 | |
10 | MARC0020616 | 57676836 | A/G | 0.050 | −0.029 | 1.32E-06 | ARMC3 | Genic | |
10 | ASGA0048292 | 57954471 | G/A | 0.050 | −0.029 | 1.32E-06 | PIP4K2A | Genic | |
10 | ASGA0048295 | 57985436 | A/G | 0.047 | −0.030 | 1.12E-06 | PIP4K2A | Genic | |
18 | MARC0096007 | 2334006 | A/G | 0.182 | −0.015 | 2.30E-06 | SHH | 330788 | |
18 | MARC0019932 | 7383149 | A/G | 0.146 | −0.017 | 6.93E-06 | ENSSSCG00000030537 | 3947 | |
18 | MARC0078684 | 7813561 | A/G | 0.138 | −0.020 | 2.53E-07* | TRBV21 | Genic | |
18 | H3GA0050297 | 7848619 | G/A | 0.138 | −0.020 | 2.53E-07* | TRBV27 | −7443 | |
X | MARC0070937 | 44930506 | G/A | 0.146 | −0.017 | 2.86E-06 | ENSSSCG00000026984 | −125815 | |
PC3 | 3 | ASGA0015307 | 98152224 | A/G | 0.150 | −0.016 | 5.57E-06 | FOXN2 | −5059 |
16 | DRGA0016097 | 36203829 | A/G | 0.072 | 0.025 | 5.45E-06 | ENSSSCG00000016898 | Genic |
MAF = Minor allele frequency.
BETA = Linear regression coefficient.
Type = ‘Genic’ means the SNP is located in genic region, value indicate direction and distance (bp) from the SNP to near genic region.
<Simple Bonfferoni significance level (1.096E-06).