Table 1.
Correlations between preoperative fibrinogen and clinicopathological parameters
| Parameters | n | Fibrinogen (g/L, mean ± SD) | P value |
| Age (yr) | |||
| < 60 | 119 | 3.29 ± 1.01 | 0.047 |
| ≥ 60 | 136 | 3.07 ± 0.73 | |
| Nationality | |||
| Han | 216 | 3.16 ± 0.87 | 0.892 |
| Uygur | 30 | 3.24 ± 0.92 | |
| Others | 9 | 3.12 ± 0.94 | |
| BMI (kg/m2) | |||
| < 18.5 | 8 | 3.54 ± 0.82 | 0.638 |
| 18.5-23.99 | 115 | 3.15 ± 0.94 | |
| 24-27.99 | 102 | 3.14 ± 0.83 | |
| ≥ 28 | 30 | 3.23 ± 0.79 | |
| Smoking | |||
| Never | 173 | 3.06 ± 0.82 | 0.018 |
| Light | 18 | 3.43 ± 0.74 | |
| Heavy | 64 | 3.39 ± 0.99 | |
| Grade (tumor differentiation) | |||
| Low | 203 | 3.12 ± 0.86 | 0.080 |
| High | 52 | 3.36 ± 0.92 | |
| TNM | |||
| I | 29 | 2.70 ± 0.58 | 0.002 |
| II | 139 | 3.24 ± 0.95 | |
| III | 87 | 3.21 ± 0.78 | |
| Tumor size (cm) | |||
| < 4 | 51 | 2.81 ± 0.72 | 0.000 |
| 4-6 | 114 | 3.01 ± 0.73 | |
| ≥ 6 | 90 | 3.57 ± 0.98 | |
| Type | |||
| Mess type | 104 | 3.13 ± 0.87 | 0.390 |
| Ulceration | 148 | 3.21 ± 0.89 | |
| Infiltrative | 3 | 2.58 ± 0.13 | |
| Tumor location | |||
| Left | 155 | 3.06 ± 0.82 | 0.020 |
| Right | 89 | 3.38 ± 0.97 | |
| Transverse | 11 | 2.99 ± 0.55 | |
| Perineural invasion | |||
| Yes | 7 | 3.40 ± 0.59 | 0.488 |
| No | 248 | 3.16 ± 0.88 | |
| Vascular invasion | |||
| Yes | 13 | 3.29 ± 0.94 | 0.619 |
| No | 242 | 3.16 ± 0.87 | |
| CEA (ng/mL) | |||
| < 5 | 161 | 3.08 ± 0.89 | 0.038 |
| ≥ 5 | 94 | 3.32 ± 0.84 | |
| AFP (ng/mL) | |||
| < 5 | 231 | 3.17 ± 0.88 | 0.747 |
| ≥ 5 | 24 | 3.11 ± 0.82 | |
| mGPS | |||
| 0 | 163 | 3.00 ± 0.77 | 0.000 |
| 1 | 71 | 3.37 ± 0.94 | |
| 2 | 21 | 3.80 ± 1.00 | |
| WBC count | |||
| < 5 × 109/L | 61 | 2.68 ± 0.56 | 0.000 |
| ≥ 5 × 109/L | 194 | 3.32 ± 0.90 | |
| NLR | |||
| < 5 | 238 | 3.13 ± 0.86 | 0.013 |
| ≥ 5 | 17 | 3.69 ± 1.02 | |
| PLR | |||
| < 150 | 134 | 2.96 ± 0.75 | 0.000 |
| 150-300 | 105 | 3.41 ± 0.96 | |
| > 300 | 15 | 3.40 ± 0.83 | |
AFP: Alpha-fetoprotein; BMI: Body mass index; CEA: Carcinoembryonic antigen; mGPS: Modified Glasgow prognostic score; NLR: Neutrophil-lymphocyte ratio; PLR: Platelet-lymphocyte ratio; TNM: Tumor-node-metastasis; WBC: White blood cell.