Table 2.
Association between PRKAA1 polymorphisms and gastric cancer
| SNP |
Dominant model |
Recessive model |
||||
| OR (95%CI) | P value1 | Q2 | OR (95%CI) | P value1 | Q2 | |
| rs6882903 | 1.48 (1.09-2.00) | 0.0121 | 0.0230 | 1.21 (0.60-2.46) | 0.5906 | 0.7383 |
| rs10074991 | 1.53 (1.09-2.16) | 0.0139 | 0.0230 | 1.47 (1.15-1.88) | 0.0021 | 0.0045 |
| rs13361707 | 1.51 (1.07-2.11) | 0.0184 | 0.0230 | 1.13 (0.43-2.92) | 0.8085 | 0.8085 |
| rs154268 | 1.65 (1.22-2.22) | 0.0012 | 0.0060 | 1.66 (1.22-2.26) | 0.0012 | 0.0045 |
| rs3805486 | 0.61 (0.34-1.09) | 0.0916 | 0.0916 | 0.63 (0.46-0.85) | 0.0027 | 0.0045 |
| VEGAS statistics (P) | 30.0356 (0.0054) | 56.0515 (0.0001) | ||||
Reference alleles of each single nucleotide polymorphism (SNP) in logistic analysis are as follows; CC for rs6882903, AA for rs10074991, and TT for rs13361707, rs154268 and rs3805486.
1
P values for logistic analysis of two alternative models (dominant and recessive) adjusted with calorie intake, smoking history, alcohol intake and educational level; 2False discovery rate Q value.