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. Author manuscript; available in PMC: 2014 Jul 11.
Published in final edited form as: Regen Med. 2010 Sep;5(5):713–724. doi: 10.2217/rme.10.60

Figure 2. Morphology of human mesenchymal stem cells and human mesenchymal cells exposed to osteogenic supplements exposed to shear stress (left to right) for 24 h.

Figure 2

Phase contrast microscopy images of (A) hMSCs and (B) hMSC-Osts not exposed to shear stress, and (C) hMSCs and (D) hMSC-Osts exposed to shear stress. hMSCs changed their fibroblast-like, spindle-shaped morphology to a more cuboidal morphology after exposure to osteogenic supplements (A vs B). There were no obvious changes in morphology of hMSCs (A vs C) and hMSC-Osts (B vs D) after 24 h exposure to 9 dynes/cm2 steady shear stress. hMSC: Human mesenchymal cell; hMSC-Osts: Human mesenchymal cells exposed to osteogenic supplement.