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Representative plaque morphologies of wild-type and mutant viruses. Vero, BD45 (UL37 expressing), FRT (UL20 expressing), and VK302 (gK expressing) cell monolayers were infected at an MOI of 0.001, and viral plaques were visualized by immunohistochemistry using polyclonal rabbit anti-HSV-1 antibody at 48 hpi.
