Comparison of in vivo replication rates for attenuated replicates and recombinant viruses. Due to housing and chick availability, recombinant viruses were tested incrementally; therefore, positive (Md5B40-c1) and negative (uninfected) controls are matched to the respective recombinant viruses tested collectively by matched symbols (i.e., *, ∧, #, etc.). Trials for Mut UL5 were conducted in duplicate, and each trial indicated is by “A” or “B.”