FIG 3.

Intestinal miRNA expression is reduced in chronically HIV-infected patients. (A) Hierarchical clustering of miRNA expression as detected by quantitative PCR in HIV-infected (n = 2) and HIV-negative (n = 2) patients. (B to D) As observed in SIV infection, the expression of miR-16, -194, and -200c is significantly reduced in the gut mucosa of HIV-infected patients (n = 5) compared to that of HIV-negative controls (n = 4). Statistical significance was determined using Student's t test. P values of ≤0.05 are denoted by *, and error bars indicate standard errors of the means.