Table 1.

The Child-Pugh Score grading system; Child-Pugh Class A = total score of 5–6, B = 7–9 and C > 9

Parameter	Score 1	Score 2	Score 3
Serum bilirubin (mg dl−1)	<2	2–3	>3
Serum albumin (g dl−1)	>3.5	2.8–3.5	<2.8
INR	<1.7	1.7–2.3	>2.3
Hepatic encephalopathy grade*	None	1–2	3–4
Ascites (grade)	Absent	Slight	Moderate

Abbreviation is as follows: INR, international normalized ratio.

^*Grade 0, normal consciousness, personality, neurological examination and electroencephalogram; Grade 1, restless, sleep-disturbed, irritable/agitated, tremor, impaired handwriting and 5 cycles per second waves; Grade 2, lethargic, time-disoriented, inappropriate, asterixis, ataxia and slow triphasic waves; Grade 3, somnolent, stuporous, place-disoriented, hyperactive reflexes, rigidity and slower waves; and Grade 4, unarousable coma, no personality/behaviour, decerebrate and slow 2–3 cycles per second delta activity. Grade 1–2 includes subjects not exhibiting clinical signs of encephalopathy because they had been treated with and were receiving stable doses of lactulose for the treatment of hepatic encephalopathy.