Table 2.
Subject demographics in the safety population, by hepatic function group
| Characteristic | Mild HI (n = 9) | Healthy match, mild HI (n = 10) | Moderate HI (n = 8) | Healthy match, moderate HI (n = 10) |
|---|---|---|---|---|
| Median age [years (range)] | 52 (36–57) | 50 (26–63) | 54.5 (52–62) | 51.5 (45–61) |
| Sex, male [n (%)] | 6 (67) | 7 (70) | 5 (63) | 7 (70) |
| Race [n (%)] | ||||
| White | 7 (78) | 7 (70) | 7 (88) | 7 (70) |
| Black or African American | 2 (22) | 2 (20) | 0 | 3 (30) |
| American Indian or Alaska Native | 0 | 0 | 1 (13) | 0 |
| Other | 0 | 1 (10) | 0 | 0 |
| Median weight [kg (range)] | 83.3 (58.0–99.4) | 84.2 (63.0–104.6) | 89.7 (64.3–106.2) | 90.2 (65.2–102.7) |
| Median BSA [m2 (range)] | 2.02 (1.64–2.19) | 1.98 (1.73–2.33) | 2.02 (1.71–2.24) | 2.09 (1.72–2.21) |
Abbreviations are as follows: BSA, body surface area; and HI, hepatic impairment.