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. 2014 May 15;289(28):19351–19363. doi: 10.1074/jbc.M114.558882

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© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 3. — (R,R′)-AminoFen exhibits β₂-AR subtype selectivity in cardiomyocyte contractile response. Single ventricular myocytes from rats were set to pace under perfusion. The contraction amplitude of a cell in response to (R,R′)-aminoFen (0.1 μm) followed by ICI-118,551 (ICI, 0.1 μm) was monitored. Steady-state contractility was recorded. Contractile response is expressed as a percentage of the basal contractility. Data are means ± S.E., n = 4 cells from four hearts. ***, p < 0.001 (by paired t test).