TABLE 1.

Basal heart rates, blood pressures, and echocardiographic parameters of Cast^−/− and Cast^+/+ mice

Values are the mean ± S.E. LVEDD, left ventricular end-diastolic dimension; LVESD, left ventricular end-systolic dimension; IVSth, intraventricular septal thickness; PWth, left ventricular posterior wall thickness; FS, fractional shortening; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; bpm, beats per min.

Parameters	Cast+/+	Cast−/−	P
Number	4	4
Age (weeks)	8.60 ± 0.08	8.60 ± 0.20	0.54
Heart rate (bpm)	640 ± 13.6	646 ± 32.6	0.79
SBP (mm Hg)	98.9 ± 5.08	97.9 ± 5.73	0.79
DBP (mm Hg)	58.2 ± 4.26	52.6 ± 3.12	0.76
LVEDD (mm)	3.48 ± 0.03	3.46 ± 0.27	0.90
LVESD (mm)	1.71 ± 0.02	1.69 ± 0.04	0.51
IVSth (mm)	0.86 ± 0.11	0.89 ± 0.04	0.62
PWth (mm)	0.81 ± 0.07	0.90 ± 0.05	0.13
FS (%)	50.7 ± 1.28	50.9 ± 2.47	0.91