Table I.
Clinical characteristics of Saudi patients with sickle cell disease of Arab-Indian Haplotype (n=104).
| Characteristics | Number of patients (%) |
|---|---|
|
| |
| Gender ratio: Male/Female | 47/57 (45/55) |
|
| |
| Mean age, years ± SD (range) | 26.9±10.6 (12-54) |
|
| |
| Folic acid supplement | 100 (96) |
|
| |
| Penicillin prophylaxis | 3 (3) |
|
| |
| Hydroxycarbamide use | 28 (27) |
|
| |
| History of painful crisis | 100 (96) |
|
| |
| Median pain episodes/year (range) | 6 (0-60) |
|
| |
| Osteonecrosis | 19 (18) |
|
| |
| Acute chest syndrome | |
| At least one episode | 49 (47) |
| Recurrent (≥2) | 16 (15) |
|
| |
| Gall stones/Cholecystectomy | 69 (66)/39 (38) |
|
| |
| Splenic sequestration | 16 (15) |
|
| |
| Splenectomy | 20 (19) |
|
| |
| Priapism | 8 (17) |
|
| |
| Leg ulcers | none |
|
| |
| Serious infections | 18 (17) |
|
| |
| Deep venous thrombosis | 4 (4) |
|
| |
| Overt stroke | 6 (6) |
|
| |
| Persistent splenomegaly n=59 | 42 (71) |