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. Author manuscript; available in PMC: 2014 Jul 11.
Published in final edited form as: J Biochem Mol Toxicol. 2009 May-Jun;23(3):202–211. doi: 10.1002/jbt.20281

TABLE 1.

Effect of E2 and BHA on Mammary Tumor Development

Treatment Group n Tumor
Incidence (%)		 Tumor
Multiplicity		 Appearance of
First Tumor (day)
Control 10 0 NA NA
Estradiol (E2) 11 82 3.1± 0.7 128
BHA 17 0 NA NA
BHA + E2 17 24* 1.0* 169

Column 1 lists different treatments each group of animals received. The number of animals per group (n) is listed in column 2. Percent tumor incidence after 240 days treatment period is listed in column 3, and the average number of tumors per tumor-bearing animal (tumor multiplicity) is listed in column 4. Column 5 contains the day on which the first tumor appeared in each group (appearance of first tumor).

*

Indicates significant difference (p < 0.05) between the E2 and E2 + BHA treated group.