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. 2014 Jul 2;12:188. doi: 10.1186/1479-5876-12-188

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Copyright © 2014 Turillazzi et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Time course of cytokine and extracellular matrix protein up-regulation in myocardial infarcts at 4hs. (A) Troponin I is markedly unexpressed in a large area of infarcted myocardium (Ab-anti TnI). (B) The confocal microscopic observation of early (4hs) myocardial infarction showed a large area of TnC depletion (in green the TnC reaction). (C) Double immunohistochemical reaction (IL-15 and CD15) evidenced an intense IL-15 (bleu) and sporadic CD15 (white) reactions in the infarcted zone. (D) Double immunohistochemical reaction (MCP-1 and CD15): MCP-1 reaction (red) is intense as well as CD15 (yellow) in the infarcted zone after 4 hrs.