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. 2014 Jul 11;9(7):e100870. doi: 10.1371/journal.pone.0100870

Table 2. Factors Predicting Survival in the Derivation Cohort.

Variable Univariate Multivariate
Hazard Ratio (95% CI) P Value Hazard Ratio (95% CI) P Value
Age 1.015 (0.995, 1.035) 0.1519
Gender 1.017 (0.507, 2.038) 0.9624
WBC, ×103/µL 1.026 (0.999, 1.055) 0.0632
ANC, ×103/µL 1.032 (1.003, 1.062) 0.0311
Hemoglobin, g/dL 0.862 (0.796, 0.933) 0.0003
Platelet, ×103/µL 0.676 (0.475, 0.963) 0.0302
Cholesterol, mg/dL 0.991 (0.986, 0.996) 0.0002
Albumin, g/dL 0.329 (0.199, 0.546) <0.0001
Total bilirubin, mg/dL 1.058 (1.033, 1.083) <0.0001 10.913 (3.649, 32.639) <0.001
AST, IU/L 0.999 (0.997, 1.001) 0.3411
ALT, IU/L 0.994 (0.988, 0.999) 0.031
ALP, IU/L 0.998 (0.995, 1.001) 0.1519
ln(PT INR) 12.35 (7.034, 21.68) <0.0001 1.049 (1.011, 1.089) <0.001
BUN, mg/dL 1.019 (1.013, 1.024) <0.0001
ln(Creatinine), mg/dL 3.353(2.545, 4.417) <0.0001 2.540 (1.757, 3.671) <0.001
Na, mmol/L 0.953 (0.925, 0.981) 0.0012
K, mmol/L 1.908 (1.530, 2.380) <0.0001 1.394 (1.090, 1.784) 0.015
SCBL, mg/dL 1.115 (1.072, 1.160) <0.0001 1.067 (1.028, 1.108) 0.001

WBC, white blood cell; ANC, absolute neutrophil count; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP. alkaline phosphatase; PT INR, international normalized ratio of prothrombin time; BUN, blood urea nitrogen; Na, sodium; K, potassium; SCBL, spontaneous change in total bilirubin levels; MAGIC, model for alcoholic hepatitis to grade severity in an Asian patient cohort.