Table 2. Factors Predicting Survival in the Derivation Cohort.
Variable | Univariate | Multivariate | ||
Hazard Ratio (95% CI) | P Value | Hazard Ratio (95% CI) | P Value | |
Age | 1.015 (0.995, 1.035) | 0.1519 | ||
Gender | 1.017 (0.507, 2.038) | 0.9624 | ||
WBC, ×103/µL | 1.026 (0.999, 1.055) | 0.0632 | ||
ANC, ×103/µL | 1.032 (1.003, 1.062) | 0.0311 | ||
Hemoglobin, g/dL | 0.862 (0.796, 0.933) | 0.0003 | ||
Platelet, ×103/µL | 0.676 (0.475, 0.963) | 0.0302 | ||
Cholesterol, mg/dL | 0.991 (0.986, 0.996) | 0.0002 | ||
Albumin, g/dL | 0.329 (0.199, 0.546) | <0.0001 | ||
Total bilirubin, mg/dL | 1.058 (1.033, 1.083) | <0.0001 | 10.913 (3.649, 32.639) | <0.001 |
AST, IU/L | 0.999 (0.997, 1.001) | 0.3411 | ||
ALT, IU/L | 0.994 (0.988, 0.999) | 0.031 | ||
ALP, IU/L | 0.998 (0.995, 1.001) | 0.1519 | ||
ln(PT INR) | 12.35 (7.034, 21.68) | <0.0001 | 1.049 (1.011, 1.089) | <0.001 |
BUN, mg/dL | 1.019 (1.013, 1.024) | <0.0001 | ||
ln(Creatinine), mg/dL | 3.353(2.545, 4.417) | <0.0001 | 2.540 (1.757, 3.671) | <0.001 |
Na, mmol/L | 0.953 (0.925, 0.981) | 0.0012 | ||
K, mmol/L | 1.908 (1.530, 2.380) | <0.0001 | 1.394 (1.090, 1.784) | 0.015 |
SCBL, mg/dL | 1.115 (1.072, 1.160) | <0.0001 | 1.067 (1.028, 1.108) | 0.001 |
WBC, white blood cell; ANC, absolute neutrophil count; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP. alkaline phosphatase; PT INR, international normalized ratio of prothrombin time; BUN, blood urea nitrogen; Na, sodium; K, potassium; SCBL, spontaneous change in total bilirubin levels; MAGIC, model for alcoholic hepatitis to grade severity in an Asian patient cohort.