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. 2014 Jul 11;9(7):e102154. doi: 10.1371/journal.pone.0102154

Table 4. Risk of ILI by Vaccine Type and Health Behavior During Two Influenza Seasons (2006/2007, 2008/2009).

Vaccine Type
LAIV TIV
Total Study Population All ILI Diagnosis All ILI Diagnosis
N ILI % N N % N N % p HR (95% CI)a
Overall 28,929 3936 13.61 22,734 3149 13.85 6195 787 12.70 0.98 (0.90–1.06)
Recent smoking history 0.099
Nonsmoker 20,974 2813 13.41 16,496 2228 13.51 4478 585 13.06 0.94 (0.85–1.03)
Smoking history 7955 1,123 14.12 6238 921 14.76 1717 202 11.76 1.09 (0.94–1.27)
Possible alcohol problems 0.209
No drinking problem 26,708 3669 13.74 21,079 2933 13.91 5629 736 13.08 0.96 (0.89–1.05)
Possible drinking problem 2221 267 12.02 1655 216 13.05 566 51 9.01 1.19 (0.86–1.63)
Exercise level 0.114
Moderate 20,345 2782 13.67 16,032 2209 13.78 4313 573 13.29 0.92 (0.84–1.01)
Minimal 3039 439 14.45 2334 348 14.91 705 91 12.91 1.08 (0.85–1.36)
High 1283 133 10.37 1007 108 10.72 276 25 9.06 1.12 (0.71–1.76)
Unknown 4262 582 13.66 3361 484 14.40 901 98 10.88 1.19 (0.96–1.48)

Abbreviations: CI, confidence interval; HR, hazard ratio; ILI, influenza-like illness; LAIV, live, attenuated influenza vaccine; TIV, trivalent inactivated influenza vaccine.

a

Hazard ratio for each health behavior stratum is evaluated at the average level of other behaviors in the study population and adjusted for all other demographic covariates.