Table 4. Risk of ILI by Vaccine Type and Health Behavior During Two Influenza Seasons (2006/2007, 2008/2009).
Vaccine Type | |||||||||||
LAIV | TIV | ||||||||||
Total Study Population | All | ILI Diagnosis | All | ILI Diagnosis | |||||||
N | ILI | % | N | N | % | N | N | % | p | HR (95% CI)a | |
Overall | 28,929 | 3936 | 13.61 | 22,734 | 3149 | 13.85 | 6195 | 787 | 12.70 | 0.98 (0.90–1.06) | |
Recent smoking history | 0.099 | ||||||||||
Nonsmoker | 20,974 | 2813 | 13.41 | 16,496 | 2228 | 13.51 | 4478 | 585 | 13.06 | 0.94 (0.85–1.03) | |
Smoking history | 7955 | 1,123 | 14.12 | 6238 | 921 | 14.76 | 1717 | 202 | 11.76 | 1.09 (0.94–1.27) | |
Possible alcohol problems | 0.209 | ||||||||||
No drinking problem | 26,708 | 3669 | 13.74 | 21,079 | 2933 | 13.91 | 5629 | 736 | 13.08 | 0.96 (0.89–1.05) | |
Possible drinking problem | 2221 | 267 | 12.02 | 1655 | 216 | 13.05 | 566 | 51 | 9.01 | 1.19 (0.86–1.63) | |
Exercise level | 0.114 | ||||||||||
Moderate | 20,345 | 2782 | 13.67 | 16,032 | 2209 | 13.78 | 4313 | 573 | 13.29 | 0.92 (0.84–1.01) | |
Minimal | 3039 | 439 | 14.45 | 2334 | 348 | 14.91 | 705 | 91 | 12.91 | 1.08 (0.85–1.36) | |
High | 1283 | 133 | 10.37 | 1007 | 108 | 10.72 | 276 | 25 | 9.06 | 1.12 (0.71–1.76) | |
Unknown | 4262 | 582 | 13.66 | 3361 | 484 | 14.40 | 901 | 98 | 10.88 | 1.19 (0.96–1.48) |
Abbreviations: CI, confidence interval; HR, hazard ratio; ILI, influenza-like illness; LAIV, live, attenuated influenza vaccine; TIV, trivalent inactivated influenza vaccine.
Hazard ratio for each health behavior stratum is evaluated at the average level of other behaviors in the study population and adjusted for all other demographic covariates.