Table 4.

Minimum requirements for transfer of patients to ERT home therapy. Adapted from (Burton et al., 2010).

Patients

Well established on idursulfase therapy Free of infusion-associated reactions Aged 2 years or older Stable airway diseasea Established IV access

Family

Should be made aware of relative risks/benefits of home therapy

Home Care Team

Meet patient prior to transfer Assess home environment prior to patient transfer Skilled in giving infusions and managing infusion-associated reactions Experienced in management of patients with LSDs Family doctor should be informed of patient transfer to ERT home therapy

^aHome treatment is contraindicated in patients with respiratory infections or other current illnesses.

ERT, enzyme replacement therapy; IV, intravenous; LSDs, lysosomal storage disorders.