Table 2.
Copy number of JH-related genes in B. mori and the other insects.
| Pathway | Gene | Symbol | B. mori (Lepidoptera) | D. melanogaster (Diptera) | A. gambiae (Diptera) | A. mellifera (Hymenoptera) | T. castaneum (Coleoptera) | D. plexippus (Lepidoptera) |
|---|---|---|---|---|---|---|---|---|
| MVA pathway of JH biosynthesis | Acetoacetyl CoA thiolase | ACAT | 1 | 1 | 1 | 1 | 1 | 1 |
| Hydroxymethylglutaryl-CoA synthase | HMGS | 1 | 1 | 1 | 1 | 1 | 1 | |
| Hydroxymethylglutaryl-CoA reductase | HMGR | 1 | 1 | 1 | 1 | 1 | 1 | |
| Mevalonate kinase | MevK | 1 | 1 | 1 | 1 | 1 | 1 | |
| Phosphomevalonate kinase | MevPK | 1 | 1 | 1 | 1 | 1 | 1 | |
| Diphosphomevalonate decarboxylase | MevPPD | 1 | 1 | 1 | 1 | 1 | 1 | |
| Isopentenyl-diphosphate delta-isomerase | IPPI | 1 | 1 | 1 | 1 | 1 | 1 | |
| Farnesyl diphosphate synthase | FPPS | 3 | 1 | 1 | 6 | 1 | 2 | |
| Isoprenoid branch of JH biosynthesis | Farnesyl phosphatase | FPPase | 2 | 1 | 1 | 2 | 3 | 2 |
| Farnesol dehydrogenase | FOHSDR | 1 | 6 | 6 | 2 | 7 | 1 | |
| Aldehyde dehydrogenase | ALDH | 2 | 1 | 1 | 1 | 6 | 2 | |
| Juvenile hormone acid methyltransferase | JHAMT | 7 | 1 | 1 | 1 | 3 | 1 | |
| Farnesoic acid O-methyltransferase |
FAMeT | 7 | 1 | 1 | 2 | 1 | 5 | |
| Cytochrome P450 15A1 | Cyp15A1 | - | - | - | 1 | 1 | - | |
| Cytochrome P450 15C1 | Cyp15C1 | 1 | - | - | - | - | 1 | |
| Neuropeptide regulation of JH biosynthesis | Allototropin | AT | 1 | - | 1 | - | 1 | 1 |
| Allatostatin | AS | 1 | 1 | 1 | 1 | 1 | 1 | |
| Allototropin receptor | ATR | 1 | 1 | 1 | 1 | 1 | 1 | |
| Allatostatin receptor | ASR | 1 | 1 | 1 | 1 | 1 | 1 | |
| JH metabolism | Juvenile hormone esterase | JHE | 4 | 2 | 2 | 2 | 1 | 1 |
| Juvenile hormone epoxide hydrolase | JHEH | 6 | 3 | 3 | 1 | 5 | 8 | |
| Juvenile hormone diol kinase | JHDK | 3 | 1 | 1 | 1 | 1 | 2 | |
| JH signaling | Juvenile hormone binding protein | JHBP | 1 | 1 | 1 | 1 | 1 | 1 |
| FKBP39 | FKBP39 | 1 | 1 | 1 | 1 | 1 | 1 | |
| Chd64 | Chd64 | 1 | 1 | 1 | 1 | 1 | 1 | |
| Methoprene-tolerant/Methoprene-tolerant 1 | Met/Met1 | 1 | 1 | 1 | 1 | 1 | 1 | |
| Germ cell expressed/Methoprene-tolerant 2 | Gce/Met2 | 1 | 1 | - | - | - | 1 | |
| Ecdysone receptor | EcR | 1 | 1 | 1 | 1 | 1 | 1 | |
| Ultraspiracle | USP | 1 | 1 | 1 | 1 | 1 | 1 | |
| Kruppel homolog 1 | Kr-h1 | 1 | 1 | 1 | 1 | 1 | 1 |
Note: - represents no identification.