Table I.
Effect of saccharin on sperm parameters, DNA integrity and apoptosis in mice
| Variables | Control group | Saccharin group | p-value |
|---|---|---|---|
| Count (×106) | 17.70 ± 1.11 | 12.80 ± 2.79 | 0.003 |
| Rapid motility (%) (Grade a) | 19.28 ± 4.53 | 9.57 ± 4.57 | 0.000 |
| Slow motility (%) (Grade b) | 21.28 ± 2.87 | 11.85 ± 3.13 | 0.000 |
| Non progressive motility (%) (Grade c) | 33.28 ± 5.12 | 35.57 ± 7.48 | 0.912 |
| Immotile sperm (%) (Grade d) | 26.14 ± 3.43 | 43.00 ± 8.08 | 0.000 |
| Total motility (%) (Grade a, b, c) | 73.85 ± 3.43 | 57.00 ± 8.08 | 0.000 |
| Normal morphology (%) | 77.00 ± 6.40 | 63.85 ± 6.81 | 0.001 |
| Viability (%) | 78.85 ± 5.36 | 60.71 ± 6.70 | 0.002 |
| TUNEL | 6.57 ± 282 | 42.85 ± 6.76 | 0.001 |
| SCD | 10.00 ± 3.74 | 47.00 ± 6.60 | 0.002 |
Post Hoc Test.
N= 7.
Data are presented as mean±SD.