Table 1.
Clinical and anthropometric characteristics of 41 pediatric CAH patients.
Variables | Salt wasters (n = 26) | Simple virilizing (n = 15) | P value |
---|---|---|---|
Age, mean (SD), years | 10.6 (4.1) | 12.8 (3.4) | 0.090 |
Obesity, n (%) | 10 (38.4) | 3 (20) | 0.381 |
Metabolic Syndrome, n (%) | 4 (15.4) | 2 (13.3) | 0.780 |
GC dose, mean (SD), mg/m2 | 9.6 (2.9) | 11.1 (4.9) | 0.428 |
Duration of GC therapy, mean (SD), years | 10.7 (4.5) | 9.3 (4.0) | 0.423 |
zBMI, mean (SD), kg/m2 | 1.04 (1.09) | 0.90 (0.74) | 0.658 |
Waist circumference, mean (SD), cm | 66.4 (11.0) | 70.8 (7.3) | 0.177 |
Hip, mean (SD), cm | 80.3 (12.9) | 88 (9.1) | 0.052 |
Hip-waist ratio, mean (SD) | 0.83 (0.06) | 0.80 (0.04) | 0.207 |
Increased waist circumference, (SD), n (%) | 13 (50) | 8 (53.3) | 0.906 |
Fasting glucose, mean (SD), mg/dL | 82.4 (8.1) | 85.1 (10.7) | 0.368 |
Fasting insulin mean (SD), μlU/mL | 12.7 (9.5) | 13.9 (10.8) | 0.548 |
HOMA-IR, mean (SD) | 1.58 (1.15) | 1.73 (1.30) | 0.547 |
HOMA-S, mean (SD) | 94.7 (58.7) | 82.1 (50.1) | 0.494 |
HOMA-B, mean (SD) | 155.0 (75.8) | 157.9 (78.8) | 0.845 |
Total cholesterol, mean (SD), mg/dL | 159.2 (33.7) | 136.6 (23.7) | 0.033 |
HDL-c, mean (SD), mg/dL | 44.2 (12.8) | 51.0 (56.6) | 0.163 |
LDL-c, mean (SD), mg/dL | 99.8 (30.7) | 75.2 (12.3) | 0.006 |
Triglycerides, mean (SD), mg/dL | 76.4 (33.0) | 52.4 (17.0) | 0.014 |
Increased blood pressure, n (%) | 2 (7.7) | 2 (13.3) | 0.968 |